Ben Gurion University of the Negev
Department of Computer Science
RNAexinv: An Extended Inverse RNA Folding from Shape and Physical Attributes to Sequences.
is an interactive java application that performs RNA sequence design, constrained to yield
a specific RNA shape and physical attributes. It is an extended inverse RNA folding program with the
rationale behind that the generated sequences should not only fold into a desired structure, but
they should also exhibit favorable attributes such as thermodynamic stability and mutational
robustness. RNAexinv considers not only the secondary structure in order to design sequences, but
also the mutational robustness and the minimum free energy. The sequences that are generated may not
fully conform with the given RNA secondary structure, but they will strictly conform with the RNA
shape of the given secondary structure and thereby take into consideration the recommended values of
thermodynamic stability and mutational robustness that are provided.
click here to download
- Extract the file with the commands:
1. >gunzip RNAexinvGUI.tar.gz
2. >tar xvf RNAexinvGUI.tar
More details on how to run the program are available here.
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