SUGGESTION 1 (D. Jones): Library of folds. Firstly it is essential that a record be made of the proteins/domains that are found in the servers' fold libraries. Clearly if a fold is not present in a fold library then this must be noted in the assessment. Of course participants have the opportunity to ensure that the appropriate folds are present given that the answers are already known (the fact that the folds are now known is of course the major fly in the ointment for CAFASP1). SUGGESTION 2 (D. Jones): Assess by structural similarity. Secondly, I think you are going to have a hard time assigning some of the SCOP numbers to the partial similarity targets. It was by no means clear how SCOP would end up assigning some of the fold identifiers to some of the targets when they are eventually added to SCOP. My feeling is that for an assessment of automated methods you should use an automated assessment! I would suggest making the assessment very simple by saying that a correct match is anything which produces a Dali Z-score of over 4.0 (or perhaps 6.0 to be safe). After all, if a structure comparison method cannot find a significant similarity then how can a fold recognition method be expected to - particularly an entirely automated method. I would certainly be _very_ happy if I could reproduce the results of Dali with a fold recognitio method. The day I can reproduce such results I will book a flight to Stockholm and start preparing my Nobel Prize speech!